Glucosylation of salicylic acid by cell suspension cultures ofMallotus japonicus
โ Scribed by Y. Umetani; E. Kodakari; T. Yamamura; S. Tanaka; M. Tabata
- Book ID
- 104675224
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 290 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0721-7714
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โฆ Synopsis
Salicylic acid was converted into its O-glucoside when administered to cell suspension cultures of Mallotus japonicus. The efficiency of the glucosylation was highest in the cells grown in Linsmaier-Skoog medium containing 1 ฮผM 2,4-dichlorophenoxy-acetic acid at any scale of culture (7 ml - 3 1). The yield of salicylic acid-O-glucoside could be increased up to 1.1 g/l by continuously dripping a non-toxic amount of salicylic acid (5.8 mg/31 medium/h) to a 51 fermenter during a culture period of 14 d.
๐ SIMILAR VOLUMES
The biotransformation of cinobufagin by cell suspension cultures of Catharanthus roseus was investigated. After 6 days incubation, four new glucosylated derivatives, desacetylcinobufagin 16-O-b-D-glucoside, 3-epi-desacetylcinobufagin 16-O-b-D-glucoside, 3-oxo-desacetylcinobufagin 16-O-b-D-glucoside,