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Glucose sensor based on a field-effect transistor with a photolithographically patterned glucose oxidase membrane

✍ Scribed by Y. Hanazato; M. Nakako; M. Maeda; S. Shiono

Book ID
104100414
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
537 KB
Volume
193
Category
Article
ISSN
0003-2670

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✦ Synopsis

A photopolymer solution consisting of polyvinylpyrrolidone and 2,5-bis(4'-azido-2'sulfobenzal)cyclopentanone is used to make a patterned glucose oxidase membrane for a FET-glucose sensor by photolithography . A small patterned glucose oxidase membrane, 0 .2 mm wide and 1 mm long, is made on the gate surface of an ISFET by developing a photocross-linked glucose oxidase membrane with aqueous 1-3% glutaraldehyde solution . The optimum composition of the enzyme/photopolymer solution is described . The sensor with the patterned membrane showed linear response to glucose concentration from 0 .3 to 2 .2 mM and useful response up to 5 mM .

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