A human ornithine decarboxylase (ODC) gene probe has been isolated from a Jurkat T-cell cDNA expression library, sequenced, and used to analyze ODC mRNA levels in untransformed human lymphocytes and fibroblasts stimulated to proliferate by various mitogens. The partial cDNA sequence is 86% homologou
Glucose elevates ornithine decarboxylase expression in vero cells
โ Scribed by David W. Lundgren; Sandra L. Prokay
- Publisher
- John Wiley and Sons
- Year
- 1988
- Tongue
- English
- Weight
- 785 KB
- Volume
- 137
- Category
- Article
- ISSN
- 0021-9541
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## Abstract Ornithine decarboxylase (ODC) can be induced up to 100โfold over basal levels four hours after addition of glutamine to the medium of HeLa cells growing in suspension culture. As demonstrated in several other cell types, ODC is inactivated very rapidly in HeLa cells, and the rate of ina
## BACKGROUND. Ornithine decarboxylase (ODC) is a key rate-limiting enzyme in polyamine biosynthesis. Several studies using an enzyme assay revealed that the ODC activity was higher in tumor tissue than in normal tissue. However, there is little information on the mRNA status of ODC in surgical sp
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