Expression of ornithine decarboxylase mRNA in gastric carcinoma
β Scribed by Masaki Mori; Masayuki Honda; Kenji Shibuta; Kinya Baba; Hideaki Nakashima; Masaru Haraguchi; Fumio Koba; Hiroaki Ueo; Keizo Sugimachi; Tsuyoshi Akiyoshi
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 422 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0008-543X
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β¦ Synopsis
BACKGROUND.
Ornithine decarboxylase (ODC) is a key rate-limiting enzyme in polyamine biosynthesis. Several studies using an enzyme assay revealed that the ODC activity was higher in tumor tissue than in normal tissue. However, there is little information on the mRNA status of ODC in surgical specimens. ODC is a transcriptional target gene of c-myc.
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