Glucocorticoid/oxysterol-induced DNA lysis in human leukemic cells
β Scribed by Betty H. Johnson; Sylvette Ayala-Torres; Lee-Nien L. Chan; Mohamed El-Naghy; E.Brad Thompson
- Book ID
- 117668814
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 929 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0960-0760
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π SIMILAR VOLUMES
The application of glucocorticoids (GC') in human leukemia is based on apoptosis induction but is often hampered by GC resistance. To delineate resistance mechanisms, we examined 5 GC-resistant leukemic cell lines, termed CEM-C7.RI-R5, isolated from the GC-sensitive human acute-1-cell-leukemic line,
The Long PCR followed by the RFLP technique has been used to search for abnormally structured mitochondrial DNA (mtDNA) and specific sequence differences implicated in the pathogenesis of acute lymphoblastic leukaemia (ALL). We have studied 54 specific sites whose combinations define groups of mtDNA