Glucocorticoid receptors and sensitivity in leukemias
✍ Scribed by Ho, A. D. ;K�nstein, W. ;Schmid, W.
- Publisher
- Springer-Verlag
- Year
- 1981
- Weight
- 538 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1432-0584
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📜 SIMILAR VOLUMES
## Abstract We have established optimal conditions for the measurement of glucocorticoid receptors (GR) in human white cells using a whole‐cell binding assay with [^3^H]dexamethasone as the ligand, and the subsequent determination of the GR content in normal human lymphocytes and in leukemic cells
## Abstract Glucocorticoid receptors were measured from leukemic cells of five patients with hairy‐cell leukemia as well as a cell line (JOK‐1) derived from one of the patients studied and grown in continuous culture __in vitro__. Receptor analyses were accomplished using a whole‐cell binding assay