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Glucocorticoid receptor (NR3C1) gene polymorphisms and onset of alcohol abuse in adolescents

✍ Scribed by Sylvane Desrivières; Anbarasu Lourdusamy; Christian Müller; Francesca Ducci; Cybele P. Wong; Marika Kaakinen; Anneli Pouta; Anna-Liisa Hartikainen; Matti Isohanni; Pimphen Charoen; Leena Peltonen; Nelson Freimer; Paul Elliott; Marjo-Riitta Jarvelin; Gunter Schumann

Book ID
110881473
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
85 KB
Volume
16
Category
Article
ISSN
1355-6215

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Glucocorticoid (GC) resistance can occur in a number of diseases. It can be either generalized (i.e., familial glucocorticoid resistance) or localized (i.e., asthma). In many cases, a reason for this resistance to steroids lies with mutations or polymorphisms present in the glucocorticoid receptor g