## Abstract We have established optimal conditions for the measurement of glucocorticoid receptors (GR) in human white cells using a wholeβcell binding assay with [^3^H]dexamethasone as the ligand, and the subsequent determination of the GR content in normal human lymphocytes and in leukemic cells
Glucocorticoid receptor localization in human epidermal cells
β Scribed by M. Serres; J. Viac; D. Schmitt
- Publisher
- Springer-Verlag
- Year
- 1996
- Tongue
- English
- Weight
- 513 KB
- Volume
- 288
- Category
- Article
- ISSN
- 0340-3696
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Glucocorticoids have been used widely in the treatment of leukemia; however, response has been variable. Glucocorticoid receptors have been implicated as the molecular basis of response to this hormonal therapy. Glucocorticoid receptor levels have been found to extend over a wide range in normal hum