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Glucocorticoid pretreatment induces cytokine overexpression and nuclear factor-κB activation in macrophages

✍ Scribed by Gordon P. Smyth; Philip P. Stapleton; Tracy A. Freeman; Erin M. Concannon; Juan R. Mestre; Michael Duff; Sirish Maddali; John M. Daly

Book ID: 117169494
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 376 KB
Volume: 116
Category: Article
ISSN: 0022-4804
DOI: 10.1016/s0022-4804(03)00300-7

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## Abstract The nuclear factor (NF)‐κB family of transcription factors plays important roles in the regulation of many activities of neuronal cells, such as synaptic transmission, inflammation, neuroprotection, and neurotoxicity. In resting cells, NF‐κB activity is present both in the cytoplasm, as