Activation of nuclear factor-κB in macrophages by mycoplasmal lipopeptides
✍ Scribed by Gudrun Sacht; Angela Märten; Ursula Deiters; Roderich Süßmuth; Günther Jung; Edgar Wingender; Peter F. Mühlradt
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 91 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0014-2980
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Nuclear factor kappa B (NF-B)/rel is the family of ubiquitous transcriptional activators involved in regulation of diverse immune and inflammatory responses. It also plays a role in control of cell growth and apoptosis. In its inactive form NF-B remains in the cytoplasm sequestered through interacti
## Abstract The nuclear factor (NF)‐κB family of transcription factors plays important roles in the regulation of many activities of neuronal cells, such as synaptic transmission, inflammation, neuroprotection, and neurotoxicity. In resting cells, NF‐κB activity is present both in the cytoplasm, as