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GLP-compliant evaluation and standardization of the peripubertal castrate male rat Hershberger assay for oral exposure of test agents

โœ Scribed by Sloan, Carol S.; Vick, Kristie D.; Kuney, Nancy M.; Fail, Patricia A.; Becker, Richard A.; Tyl, Rochelle W.


Book ID
123439832
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
597 KB
Volume
35
Category
Article
ISSN
0890-6238

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โœ J. Ashby; P. A. Lefevre ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 142 KB

A range of chemicals with various levels of activity as actual or potential endocrine disrupters have been evaluated for activity in the peripubertal male rat assay. The chemicals studied included anti-androgens (vinclozolin), cyproterone acetate, flutamide, 2, 2-bis(4-chlorophenyl)-1,1-dichloroethy