## Abstract ## Background T2DM is a complex metabolic disease. Genetic studies on T2DM have been of little help so far because several genetic association studies have shown conflicting results. In this study, we report the findings of a case‐control study on three SNPs in the GLUT1 gene. For this
✦ LIBER ✦
Globular adiponectin stimulates glucose transport in type 2 diabetic muscle
✍ Scribed by Heidi Kuoppamaa; Paulina Skrobuk; Maarit Sihvo; Anne Hiukka; Alexander V. Chibalin; Juleen R. Zierath; Heikki A. Koistinen
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 157 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1520-7552
- DOI
- 10.1002/dmrr.883
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## Abstract Elevated extracellular D‐glucose increases transforming growth factor β1 (TGF‐β1) release from human umbilical vein endothelium (HUVEC). TGF‐β1, via TGF‐β receptors I (TβRI) and TβRII, activates Smad2 and mitogen‐activated protein kinases p44 and p42 (p42/44^mapk^). We studied whether D