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Globin Synthesis and Erythroid Differentiation in a Friend Cell Variant Deficient in Heme Synthesis

โœ Scribed by T. R. Rutherford and P. R. Harrison

Book ID
123656169
Publisher
National Academy of Sciences
Year
1979
Tongue
English
Weight
836 KB
Volume
76
Category
Article
ISSN
0027-8424

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## Abstract Synthesis of globin mRNA in erythroid spleen cells from anemic mice was measured after in vitro incubation under conditions in which the level of intracellular heme was manipulated. This newly synthesized globin mRNA was isolated by hybridization with globin cDNA covalently bound to cel