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Global histone H3 lysine 27 (H3K27) methylation levels and their prognostic relevance in renal cell carcinoma

✍ Scribed by Sebastian Rogenhofer; Philip Kahl; Claudia Mertens; Stefan Hauser; Wolfgang Hartmann; Reinhard Büttner; Stefan C. Müller; Alexander von Ruecker; Jörg Ellinger

Book ID
110923755
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
471 KB
Volume
109
Category
Article
ISSN
1464-4096

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✍ Jörg Ellinger; Philip Kahl; Claudia Mertens; Sebastian Rogenhofer; Stefan Hauser 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 French ⚖ 392 KB

## Abstract Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Our study was performed to evaluate histone H3 lysine 4 mono‐methyl (H3K4me1), ‐di‐methyl (H3K4me2)