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Expression and significance of histone H3K27 demethylases in renal cell carcinoma

✍ Scribed by Yongqing Shen, Xiaoqiang Guo, Yuejia Wang, Wei Qiu, Yanzhong Chang, Aili Zhang, Xianglin Duan

Book ID: 119897508
Publisher: BioMed Central
Year: 2012
Tongue: English
Weight: 437 KB
Volume: 12
Category: Article
ISSN: 1471-2407
DOI: 10.1186/1471-2407-12-470

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## Abstract Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Our study was performed to evaluate histone H3 lysine 4 mono‐methyl (H3K4me1), ‐di‐methyl (H3K4me2)