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Global DNA hypomethylation increases progressively in cervical dysplasia and carcinoma

✍ Scribed by Young-In Kim; Anna Giuliano; Kenneth D. Hatch; Achim Schneider; Magdy A. Nour; Gerard E. Dallal; Jacob Selhub; Joel B. Mason


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
719 KB
Volume
74
Category
Article
ISSN
0008-543X

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Global DNA hypomethylation in breast car
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## BACKGROUND. The global DNA methylation of 136 breast lesions (117 primary invasive carcinomas, 5 benign phyllodes tumors, 11 fibroadenomas, and 3 sclerosing adenosis) and their respective adjacent parenchyma was analyzed using an in vitro enzyme assay. ## METHODS. In the group of patients wi