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Global distribution and reduced penetrance: Lrrk2 R1441C in an Irish Parkinson's disease kindred

✍ Scribed by David Gosal; Timothy Lynch; Owen A. Ross; Kristoffer Haugarvoll; Matthew J. Farrer; J. Mark Gibson


Book ID
102504820
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
106 KB
Volume
22
Category
Article
ISSN
0885-3185

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## Abstract The frequency and penetrance of the LRRK2 G2019S mutation varies considerably in different Parkinson disease (PD) populations. This information is essential both for clinical purposes and genetic counseling. The objective of this study was to estimate the prevalence and penetrance of th