A specific and quantitative assay for determining nanogram levels of nitroglycerin in plasma was developed. The method involves stabilization of the drug in plasma with silver nitrate, followed by multiple extraction using purified hexane. Isosorbide dinitrate is added as the internal standard. The
GLC determination of plasma concentrations of phenprocoumon
โ Scribed by K. K. Midha; J. W. Hubbard; J. K. Cooper; I. J. McGilveray
- Publisher
- John Wiley and Sons
- Year
- 1976
- Tongue
- English
- Weight
- 497 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
โฆ Synopsis
jected intraperitoneally for 5 days, starting on the 1st day after tumor transplantation (Fig. ). On this resistant line, 5-fluorodeoxyuridine had no effect a t this level while I still inhibited tumor growth. Obviously, the effects of other nucleoside phosphodiesters whose action also would be aided by high levels of phosphodiesterase in these resistant tumors should be studied.
๐ SIMILAR VOLUMES
I J A simple GLC method was developed for the determination of methaqualone in plasma. The method is rapid and quantitative over the 0.1-1 .O-mcg./ml. range. KeyphrPsee 0 Methaqualone-GLC determination in plasma 0 GLC-determination of methaqualone in plasma
Implementation of human bioavailability studies with the analgesic indoprofen required a rapid, sensitive, and convenient assay in blood plasma. A procedure based on ether extraction of acidified plasma, derivatization with diazomethane, and GLC analysis using a 3% OV-1 column was sufficiently sensi