Glaser oxidative coupling in ionic liquids: an improved synthesis of conjugated 1,3-diynes

✍ Scribed by J.S. Yadav; B.V.S. Reddy; K.Bhaskar Reddy; K.Uma Gayathri; A.R. Prasad

• Book ID: 104254179
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 184 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)01565-x

✦ Synopsis

Terminal alkynes undergo oxidative-coupling smoothly in the presence of the CuCl-TMEDA catalytic system in hydrophobic [bmim]PF 6 ionic liquid under aerobic conditions to produce 1,3-diynes in excellent yields under mild conditions. The substrates, alkynes, show enhanced reactivity and selectivity in ionic liquids (ILs). The recovery of the catalyst is facilitated by the hydrophobic nature of the [bmim]PF 6 ionic liquid.