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GG genotype of cyclin D1 G870A polymorphism is associated with increased risk and advanced colorectal cancer in patients in Singapore

✍ Scribed by Yi Hong; Kong Weng Eu; Francis Seow-Choen; Stephanie Fook-Chong; Peh Yean Cheah


Book ID
116428483
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
195 KB
Volume
41
Category
Article
ISSN
0959-8049

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## Abstract __CCND1__ mRNA is alternatively spliced to produce 2 transcripts, and the splicing pattern may be modulated by a frequent __A__870__G__ single‐nucleotide polymorphism within the conserved splice donor site of exon 4. Several studies have suggested a significant association between the _