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Germline pharmacogenomics in oncology: Decoding the patient for targeting therapy

✍ Scribed by Peter H. O'Donnell; Mark J. Ratain

Book ID
119328964
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
240 KB
Volume
6
Category
Article
ISSN
1574-7891

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## Abstract ## BACKGROUND. The mammalian target of rapamycin (mTOR) pathway is up‐regulated in many human cancers, and agents targeting the mTOR pathway are in various stages of clinical development. The goal of the study was to evaluate the potential and limitations of targeting the mTOR pathway