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Key considerations in patient selection for the use of targeted therapy in metastatic renal cell carcinoma

✍ Scribed by Alain Ravaud


Book ID
118624954
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
505 KB
Volume
5
Category
Article
ISSN
1359-6349

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Prognostic relevance of the mTOR pathway
✍ Allan J. Pantuck; David B. Seligson; Tobias Klatte; Hong Yu; John T. Leppert; La πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 980 KB

## Abstract ## BACKGROUND. The mammalian target of rapamycin (mTOR) pathway is up‐regulated in many human cancers, and agents targeting the mTOR pathway are in various stages of clinical development. The goal of the study was to evaluate the potential and limitations of targeting the mTOR pathway