𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Germline mutations of the APC gene in two Japanese adenomatous polyposis patients

✍ Scribed by Yoshinori Nimura; Chizumi Furuwatari; Minoru Fujimori; Yoshiro Fujimori; Shinji Nakata; Ken-ichi Ito; Yoshihisa Hama; Kiyoshi Shingu; Wataru Adachi; Yoshifumi Ogiso; Ken-ichi Furihata; Tsutomu Katsuyama; Jun Amano


Book ID
110676785
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
381 KB
Volume
42
Category
Article
ISSN
1435-232X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


APC germline mutations identified in Cze
✍ Milada KohoutovΓ‘; Jitka Ε tekrovΓ‘; VΓ‘clav JirΓ‘sek; Jan Kapras πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 157 KB πŸ‘ 2 views

## Communicated by Georgia Chenevix-Trench Familial adenomatous polyposis (FAP) is an autosomal dominantly inherited predisposition to colorectal cancer, which is caused by germline mutations in the adenomatous polyposis coli (APC) gene. The APC mutations have been investigated in 46 Czech unrelat

Characterization of two novel adenomatou
✍ Bharati Bapat; Terri Berk; Angela Mitri; Zane Cohen; Steven Gallinger; Hartley S πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 398 KB πŸ‘ 2 views

Patients with Familial Adenomatous Polyposis (FAP) manifest numerous colorectal adenomas as well as benign and malignant extra-colonic lesions. Adenomatous polyposis coli (APC) gene mutations are the underlying genetic defect in FAP. We analyzed germline D N A of 81 unrelated FAP patients and evalua

Mutations of the APC adenomatous polypos
✍ Hiroki Nagase; Yusuke Nakamura πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 823 KB

Several investigators have reported germline mutations of the APC gene in patients with familial adenomatous polyposis (FAP) as well as somatic mutations in tumors developed in digestive organs (stomach, pancreas, colon, and rectum). Those results provide evidence that inactivation of the APC gene p

Mutation analysis of the adenomatous pol
✍ Marie Luise Bisgaard; RASMUS S. Ripa; Steffen BΓΌlow πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 26 KB πŸ‘ 2 views

## Development of one hundred or more adenomas in the colon and rectum is diagnostic for the dominantly inherited, autosomal disease Familial Adenomatous Polyposis (FAP). It is possible to identify a mutation in the Adenomatous Polyposis Coli (APC) gene in approximately 80% of the patients, and alm