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Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer

✍ Scribed by Miyaki, Michiko; Konishi, Motoko; Tanaka, Kiyoko; Kikuchi-Yanoshita, Rei; Muraoka, Masatoshi; Yasuno, Masamichi; Igari, Tohru; Koike, Morio; Chiba, Mitsuro; Mori, Takeo


Book ID
109918650
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
250 KB
Volume
17
Category
Article
ISSN
1061-4036

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## Abstract HNPCC is an autosomal dominantly inherited cancer‐susceptibility syndrome that confers an increased risk for colorectal cancer and endometrial cancer at a young age. It also entails an increased risk of a variety of other tumors, such as ovarian, gastric, uroepithelial and biliary tract