𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Geraniol and β-ionone inhibit proliferation, cell cycle progression, and cyclin-dependent kinase 2 activity in MCF-7 breast cancer cells independent of effects on HMG-CoA reductase activity

✍ Scribed by Robin E. Duncan; Dominic Lau; Ahmed El-Sohemy; Michael C. Archer

Book ID
113487302
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
368 KB
Volume
68
Category
Article
ISSN
0006-2952

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Geraniol and β-ionone inhibit proliferat
Geraniol and β-ionone inhibit proliferation, cell cycle progression, and cyclin-dependent kinase 2 activity in MCF-7 breast cancer cells independent of effects on HMG-CoA reductase activity
✍ Robin E. Duncan; Dominic Lau; Ahmed El-Sohemy; Michael C. Archer 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 368 KB

3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase catalyzes the formation of mevalonate, a precursor of cholesterol that is also required for cell proliferation. Mevalonate depletion results in a G1 phase cell cycle arrest that is mediated in part by impaired activity of cyclin-dependent kin