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Corrigendum to “Geraniol and β-ionone inhibit proliferation, cell cycle progression, and cyclin-dependent kinase 2 activity in MCF-7 breast cancer cells independent of effects on HMG-CoA reductase activity” [Biochem. Pharmacol. 68 (2004) 1739–1747]

✍ Scribed by Robin E. Duncan; Dominic Lau; Ahmed El-Sohemy; Michael C. Archer


Book ID
113487447
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
42 KB
Volume
69
Category
Article
ISSN
0006-2952

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Geraniol and β-ionone inhibit proliferat
✍ Robin E. Duncan; Dominic Lau; Ahmed El-Sohemy; Michael C. Archer 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 368 KB

3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase catalyzes the formation of mevalonate, a precursor of cholesterol that is also required for cell proliferation. Mevalonate depletion results in a G1 phase cell cycle arrest that is mediated in part by impaired activity of cyclin-dependent kin