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Geometry of the five-membered ring mathematical demonstration of the pseudorotation formulae

✍ Scribed by E. Abillon

Publisher
Springer
Year
1982
Tongue
English
Weight
524 KB
Volume
8
Category
Article
ISSN
1432-1017

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Novel Approach for the Synthesis of Five
Novel Approach for the Synthesis of Five-Membered-Ring-Fused Pyrazinones
✍ Vincent Gembus; Solenn Janvier; Jean-Pierre LecouvΓ©; Philippe Gloanec; Francis M πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 114 KB

## Abstract We describe a new route to access important pharmaceutical intermediates for the synthesis of constrained fused pyrazinones. These compounds are prepared in five to seven steps with a good overall yield from glycine methyl ester and commercial propanediol derivatives involving an intram