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Genotypic analysis of Asp299Gly and Thr399Ile polymorphism of Toll-like receptor

✍ Scribed by Eun-Suk Kang; Jisoo Lee


Book ID
106007293
Publisher
Springer
Year
2007
Tongue
English
Weight
199 KB
Volume
27
Category
Article
ISSN
0172-8172

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## Abstract A nonsynonymous single nucleotide polymorphism (Asp299Gly) in the __Toll‐like receptor‐4__ (__TLR‐4__) gene affects the responsiveness to lipopolysaccharide in humans. To analyze this important polymorphism more efficiently, we developed a simple polymerase chain reaction (PCR) restrict