Cell-transforming activity and genotoxic
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Takeki Tsutsui; Yukiko Tamura; Eiichi Yagi; Koko Hasegawa; Yuriko Tanaka; Akira
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Article
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1997
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John Wiley and Sons
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French
β 83 KB
Phenolphthalein is a cathartic agent widely used in nonprescription laxatives. For the simultaneous assessment of in vitro carcinogenicity and mutagenicity of phenolphthalein, the ability of this chemical to induce cell transformation and genetic effects was examined using the Syrian hamster embryo