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Evaluation of the carcinogenic and genotoxic potential of praziquantel in the Syrian hamster embryo cell transformation assay

✍ Scribed by Luis A. Herrera; Patricia Ostrosky-Wegman; Regina Montero; Emilio Rojas; María E. Gonsebatt; Dietmar Schiffmann

Book ID
113194655
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
462 KB
Volume
305
Category
Article
ISSN
0027-5107

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Phenolphthalein is a cathartic agent widely used in nonprescription laxatives. For the simultaneous assessment of in vitro carcinogenicity and mutagenicity of phenolphthalein, the ability of this chemical to induce cell transformation and genetic effects was examined using the Syrian hamster embryo