Genomics in Cancer Drug Discovery and Development

✍ Scribed by Garret M. Hampton, Karol Sikora, George F. Vande Woude and George Klein (Eds.)

Publisher: Academic Press, Elsevier
Year: 2006
Leaves: 418
Series: Advances in Cancer Research 96
Category: Library

No coin nor oath required. For personal study only.

✦ Table of Contents

Content:
Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches Review Article
Pages 1-22
Samuel C. Mok, Kevin M. Elias, Kwong‐Kwok Wong, Kae Ho, Tomas Bonome, Michael J. Birrer

Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics Review Article
Pages 23-50
Da‐Elene van der Merwe, Katerina Oikonomopoulou, John Marshall, Eleftherios P. Diamandis

Microarrays to Identify New Therapeutic Strategies for Cancer Review Article
Pages 51-74
Christopher Sears, Scott A. Armstrong

The Application of siRNA Technology to Cancer Biology Discovery Review Article
Pages 75-102
Uta Fuchs, Arndt Borkhardt

Ribozyme Technology for Cancer Gene Target Identification and Validation Review Article
Pages 103-143
Qi‐Xiang Li, Philip Tan, Ning Ke, Flossie Wong‐Staal

Cancer Cell‐Based Genomic and Small Molecule Screens Review Article
Pages 145-173
Jeremy S. Caldwell

Practices and Pitfalls of Mouse Cancer Models in Drug Discovery Review Article
Pages 191-212
Andrew L. Kung

Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics Review Article
Pages 213-268
Debashis Sarker, Paul Workman

Tumor Antigens as Surrogate Markers and Targets for Therapy and Vaccines Review Article
Pages 175-190
Angus Dalgleish, Hardev Pandha

Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development: Quantification of Emerging Protein Biomarkers Review Article
Pages 269-298
Jean W. Lee, Daniel Figeys, Julian Vasilescu

Molecular Optical Imaging of Therapeutic Targets of Cancer Review Article
Pages 299-344
Konstantin Sokolov, Dawn Nida, Michael Descour, Alicia Lacy, Matthew Levy, Brad Hall, Su Dharmawardhane, Andrew Ellington, Brian Korgel, Rebecca Richards‐Kortum

Cancer Drug Approval in the United States, Europe, and Japan Review Article
Pages 371-391
R.A.V. Milsted

Personalized Medicine for Cancer: From Molecular Signature to Therapeutic Choice Review Article
Pages 345-369
Karol Sikora

Contents
Pages V-IX

Contributors to Volume 96
Pages XI-XIII

Index
Pages 393-409

Introduction
Pages XV-XIX
Garret M. Hampton, Karol Sikora

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