Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia of the lower limbs. Autosomal dominant hereditary spastic paraplegia 4 linked to chromosome 2p (SPG4) is the most co
Genomic structure and expression analysis of the spastic paraplegia gene, SPG7
β Scribed by C. Settasatian; S.A. Whitmore; J. Crawford; R.L. Bilton; A.-M. Cleton-Jansen; G.R. Sutherland; D.F. Callen
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 249 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0340-6717
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Hereditary spastic paraplegias (HSP) comprise a genetically and clinically heterogeneous group of neurodegenerative disorders characterised by progressive spasticity and hyperreflexia of the lower limbs. Autosomal dominant hereditary spastic paraplegia linked to the SPG3A locus on chromosome 14q11-2