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The genomic structure and expression ofMJD, the Machado-Joseph disease gene

✍ Scribed by Y. Ichikawa; J. Goto; M. Hattori; A. Toyoda; K. Ishii; S.-Y. Jeong; H. Hashida; N. Masuda; K. Ogata; F. Kasai; M. Hirai; P. Maciel; G. A. Rouleau; Y. Sakaki; I. Kanazawa


Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
283 KB
Volume
46
Category
Article
ISSN
1435-232X

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Ethnic differences in the expression of
✍ S.H. Subramony; Dena Hernandez; Amanda Adam; Stephanie Smith-Jefferson; Jennifer πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 65 KB

## Abstract We describe several families of African origin with SCA3/Machado‐Joseph disease gene expansions. In these cases, the phenotype ranges from ataxia with parkinsonian signs to a syndrome clinically almost indistinguishable from idiopathic, L‐dopa–responsive Parkinson's disease. In contrast