Genomic profiling of high-risk acute lymphoblastic leukemia
โ Scribed by Collins-Underwood, J R; Mullighan, C G
- Book ID
- 109887219
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 628 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0887-6924
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## Abstract In acute lymphoblastic leukemia (ALL) specific genomic abnormalities provide important clinical information. In most routine clinical diagnostic laboratories conventional karyotyping, in conjunction with targeted screens using e.g., fluorescence in situ hybridization (FISH), is currentl
Sixteen children with high risk acute lymphoblastic leukemia (ALL) who had one or more of the following risk factors: white cell count over 50 x 10g/liter, mediastinal mass, age under 2 or over 10 years, extramedullary involvement, or T-cell markers, were treated by a new protocol. All attained comp