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Genomic organization of the channel catfish CD45 functional gene and CD45 pseudogenes

✍ Scribed by Evgueni Kountikov; Melanie Wilson; Sylvie Quiniou; Norman Miller; William Clem; Eva Bengtén


Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
853 KB
Volume
57
Category
Article
ISSN
0093-7711

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The role of the CD45-associated phosphoprotein (LPAP/CD45-AP) during an immune response remains unclear. To understand better the function of LPAP we generated LPAPdeficient mice by disrupting exon 2 of the LPAP gene. LPAP-null mice were healthy and did not show gross abnormalities compared to their