Genomic instability, as demonstrated by the presence of additional alleles at short tandemly repeated (STR) loci, has recently been observed in colorectal tumours from individuals with hereditary nonpolyposis colorectal cancer (HNPCC), and in some sporadic tumours. These neoplasms have been called r
Genomic Instability in Pituitary Adenomas
β Scribed by Janusz Szymas; Karsten Schluens; Wlodzimierz Liebert; Iver Petersen
- Book ID
- 111549512
- Publisher
- Springer US
- Year
- 2002
- Tongue
- English
- Weight
- 747 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1386-341X
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## Abstract Angiogenesis, which is the formation of new blood vessels from preexisting capillaries, plays an important role in tumor growth and metastasis. In this review, the focus is on angiogenesis in pituitary adenomas. Angiogenesis of pituitary adenomas has been assessed by studying tumor micr
Twenty-four pituitary adenomas, both the sporadic type (n ΒΌ 18) and the type arising in association with either multiple endocrine neoplasia, type 1 (MEN1; n ΒΌ 2), or Carney complex (CNC, n ΒΌ 4) were analyzed by comparative genomic hybridization. Twenty-one (88%) tumors displayed chromosomal alterat