Genomic instability and cancer: Lessons learned from human papillomaviruses
β Scribed by Nina Korzeniewski; Nicole Spardy; Anette Duensing; Stefan Duensing
- Book ID
- 116335552
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 610 KB
- Volume
- 305
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Genomic instability is a hallmark of most human cancers including highβrisk human papillomavirus (HPV)βassociated anogenital neoplasia. The two HPVβencoded oncoproteins, E6 and E7, can independently induce chromosomal abnormalities. We summarize the current state of knowledge concerning