Genome-wide measurement of RNA secondary structure in yeast
β Scribed by Kertesz, Michael; Wan, Yue; Mazor, Elad; Rinn, John L.; Nutter, Robert C.; Chang, Howard Y.; Segal, Eran
- Book ID
- 109899118
- Publisher
- Nature Publishing Group
- Year
- 2010
- Tongue
- English
- Weight
- 590 KB
- Volume
- 467
- Category
- Article
- ISSN
- 0028-0836
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The thermodynamics of RNA secondary structure formation in small model systems provides a database for predicting RNA structure from sequence. Methods for making these measurements are reviewed with emphasis on optical methods and treatment of experimental errors. Analysis of experimental results in
## Abstract With more and more RNA secondary structures accumulated, the need for comparing different RNA secondary structures often arises in function prediction and evolutionary analysis. Numerous efficient algorithms were developed for comparing different RNA secondary structures, but challenges