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Genome-wide association study for C-reactive protein levels identified pleiotropic associations in the IL6 locus

✍ Scribed by Okada, Y.; Takahashi, A.; Ohmiya, H.; Kumasaka, N.; Kamatani, Y.; Hosono, N.; Tsunoda, T.; Matsuda, K.; Tanaka, T.; Kubo, M.; Nakamura, Y.; Yamamoto, K.; Kamatani, N.


Book ID
121738824
Publisher
Oxford University Press
Year
2010
Tongue
English
Weight
191 KB
Volume
20
Category
Article
ISSN
0964-6906

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A genome-wide association study for celi
✍ van Heel, David A; Franke, Lude; Hunt, Karen A; Gwilliam, Rhian; Zhernakova, Ale πŸ“‚ Article πŸ“… 2007 πŸ› Nature Publishing Group 🌐 English βš– 211 KB

We tested 310,605 SNPs for association in 778 individuals with celiac disease and 1,422 controls. Outside the HLA region, the most significant finding (rs13119723; P ΒΌ 2.0 Γ‚ 10 -7 ) was in the KIAA1109-TENR-IL2-IL21 linkage disequilibrium block. We independently confirmed association in two further