## Abstract In order to identify genes or regions involved in nonsyndromic cleft lip with or without cleft palate (CL/P) in families from India, we analyzed 38 multiplex families (DNA from 272 individuals, 82 affected with CL/P, 190 unaffected) for 285 genomeβwide markers (average spacing 12.6 cM),
Genome-wide and Interaction Linkage Scan for Nonsyndromic Cleft Lip with or without Cleft Palate in Two Multiplex Families in Shenyang, China
β Scribed by Yun WANG; Xin LI; Wen-Li ZHU; Jin-Zhen GUO; Xiao-Ming SONG; Shu-Qin LI; Yong LI
- Book ID
- 117596769
- Publisher
- Chinese Electronic Periodical Services
- Year
- 2010
- Tongue
- English
- Weight
- 510 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0895-3988
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## Abstract Nonβsyndromic cleft lip with/without cleft palate (CL/P) is a common, usually nonβfatal birth defect of complex etiology. Several segregation analyses have demonstrated that genetic factors are important in the pathogenesis of CL/P, most likely through the interaction of several genes o
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