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Genome-wide analyses on loss of heterozygosity in hepatocellular carcinoma in Southern China

โœ Scribed by Sheng-Ping Li; Hui-Yun Wang; Jing-Qin Li; Chang-Qing Zhang; Qi-Sheng Feng; Ping Huang; Xin-Juan Yu; Li-Xi Huang; Qi-Wang Liang; Yi-Xin Zeng


Book ID
119526575
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
476 KB
Volume
34
Category
Article
ISSN
0168-8278

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We investigated 24 hepatocellular carcinomas in Japan to find loss of heterozygosity with 15 polymorphic DNA markers that detect allelic losses at specific chromosome loci. Loss of heterozygosity on chromosomes lOq, 17p and 22q was detected in 3 of 12 (26%), 9 of 21 (43%) and 5 of 15 (33%) informati

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