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Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma

✍ Scribed by Zhang, Wandong ;Hirohashi, Setsuo ;Tsuda, Hitoshi ;Shimosato, Yukio ;Yokota, Jun ;Terada, Masaaki ;Sugimura, Takashi

Book ID
108579018
Publisher
Wiley (Blackwell Publishing)
Year
1990
Tongue
English
Weight
257 KB
Volume
81
Category
Article
ISSN
0910-5050

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## Abstract Frequent loss of heterozygosity (LOH) on both arms of chromosome 17 has been described in ovarian carcinoma (OC) by a number of groups, and the recent fine mapping of an inherited breast‐ovarian cancer gene (__brc__Al) to a small region at 17q 12–21 has focused interest on this area. We