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GenoMass software: a tool based on electrospray ionization tandem mass spectrometry for characterization and sequencing of oligonucleotide adducts

✍ Scribed by Vaneet K Sharma; James Glick; Qing Liao; Chang Shen; Paul Vouros


Book ID
112133163
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
906 KB
Volume
47
Category
Article
ISSN
1076-5174

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## Abstract Endogenous carcinogens arising from normal metabolism are known to cause modifications to DNA by reacting with bases to form adducts. Malondialdehyde is a well characterized endogenous carcinogen that forms an adduct with 2′‐deoxyguanosine. This adduct has been detected in rat and human