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Genistein Inhibits Constitutive and Inducible NFκB Activation and Decreases IL-8 Production by Human Cystic Fibrosis Bronchial Gland Cells

✍ Scribed by Olivier Tabary; Sandie Escotte; Jean Paul Couetil; Dominique Hubert; Daniel Dusser; Edith Puchelle; Jacky Jacquot

Book ID
117022559
Publisher
American Society for Investigative Pathology
Year
1999
Tongue
English
Weight
873 KB
Volume
155
Category
Article
ISSN
0002-9440

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## Abstract ## Background Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Neutrophil‐dominated inflammation and chronic bacterial infection are still considered the primary cause of bronchioectasis, respiratory failure and consequ