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Genistein analogues: effects on epidermal growth factor receptor tyrosine kinase and on stress-activated pathways

✍ Scribed by M Croisy-Delcey; A Croisy; S Mousset; M Letourneur; E Bisagni; A Jacquemin-Sablon; J Pierre

Book ID
117575982
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
865 KB
Volume
51
Category
Article
ISSN
0753-3322

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## Abstract The epidermal growth factor (EGF) and __erb__B‐2 receptors are structurally related membrane‐bound tyrosine kinases. While these proteins exhibit close sequence homology, 50% overall and 80% in the tyrosine kinase domains, they respond very differently to heat stress. In NIH‐3T3 or NR6