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Genetics of human left–right axis malformations

✍ Scribed by Kenjiro Kosaki; Brett Casey


Book ID
115647349
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
234 KB
Volume
9
Category
Article
ISSN
1084-9521

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Left-right axis malformations associated
✍ Kosaki, Rika; Gebbia, Marinella; Kosaki, Kenjiro; Lewin, Mark; Bowers, Peter; To 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 54 KB 👁 1 views

Targeted disruption of the mouse activin receptor type IIB gene (Acvr2b) results in abnormal left-right (LR) axis development among Acvr2b-/- homozygotes [Oh and Li, 1997: Genes Dev 11:1812-1826]. The resulting malformations include atrial and ventricular septal defects, right-sided morphology of th