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Genetics and molecular biology of Huntington's disease

✍ Scribed by Roger L. Albin; Danilo A. Tagle


Book ID
116103997
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
593 KB
Volume
18
Category
Article
ISSN
0166-2236

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Molecular aspects of Huntington's diseas
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Huntington's disease (HD) is a progressive neurodegenerative disease striking principally medium spiny GABAergic neurons of the caudate nucleus of the basal ganglia. It affects about one in 10,000 individuals and is transmitted in an autosomal dominant fashion. The molecular basis of the disease is