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Genetically modified human embryonic stem cells relieve symptomatic motor behavior in a rat model of Parkinson's disease

✍ Scribed by Sepill Park; Eun Young Kim; Gwang Su Ghil; Wan Seok Joo; Kyu Chang Wang; Yong Sik Kim; Young Jae Lee; Jinho Lim


Book ID
116766071
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
168 KB
Volume
353
Category
Article
ISSN
0304-3940

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## Abstract Parkinson's disease (PD) is a neurodegenerative disease characterized by progressive degeneration of nigrostriatal dopaminergic (DA) neurons. The therapeutic potential of glial cell line‐derived neurotrophic factor (GDNF), the most potent neurotrophic factor for DA neurons, has been dem