Genetically determined sparteine oxidati
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K. Orzechowska-Juzwenko; J. Pawlik; P. Niewiński; P. Milejski; J. Dembowski; J.
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Article
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1994
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Springer
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English
⚖ 259 KB
The genetic oxidation polymorphism was determined in 160 healthy Polish volunteers from the southwest of Poland (Wroctaw region), using sparteine as a model drug. The results of a Polish population study revealed a bimodal distribution of the sparteine metabolic ratio and showed the existence of two