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Genetic variation in renin predicts the effects of thiazide diuretics

✍ Scribed by Chin-Chou Huang; Chia-Min Chung; Shuen-Iu Hung; Hsin-Bang Leu; Tao-Cheng Wu; Po-Hsun Huang; Shing-Jong Lin; Wen-Harn Pan; Jaw-Wen Chen


Book ID
108714138
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
117 KB
Volume
41
Category
Article
ISSN
0014-2972

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The effect of the thiazide diuretic, bemetizide, on the excretion of Na +, K +, CI-, Ca 2 +, and Mg 2 Γ· in relation to the glomerular filtration rate (GFR) was studied in 17 subjects whose creatinine clearances ranged from 133 to 5 ml. min-1. After a 2-day fluid and salt balanced control period, 25